Publications

Alteen, M. G., Gros, C., Meek, R. W., Cardoso, D. A., Busmann, J. A., Sangouard, G., Deen, M. C., Tan, H.-Y., Shen, D. L., Russell, C. C., Davies, G. J., Robinson, P. J., McCluskey, A., & Vocadlo, D. J. (2020). A Direct Fluorescent Activity Assay for Glycosyltransferases Enables Convenient High-Throughput Screening: Application to O-GlcNAc Transferase. Angewandte Chemie (International Ed. in English), 59(24), 9601–9609. https://doi.org/10.1002/anie.202000621

Ashmus, R., Wang, Y., Cuesta, M., Gilormini, P.-A., Tiet, B., King, D., Garcia Fernandez, J., Mellet, C., Britton, R., & Vocadlo, D. (2020). Rationale design and synthesis of cell active selective inhibitors of human ɑ-galactosidase (GALA). In press.

 

Cecioni, S., Ashmus, R., Gilormini, P.-A., Zhu, S., Shan, X., Gros, C., Deen, M., Wang, Y., Britton, R., & Vocadlo, D. (2020). Quantitative monitoring of glycosidase activity in live cells using sensitive fluorescence-quenched bis-acetal substrates. Revision requested.

 

Challa, V. R., Kwon, D., Taron, M., Fan, H., Kang, B., Wilson, D., Haeckl, F. P. J., Keerthisinghe, S., Linington, R. G., & Britton, R. (2021). Total synthesis of biselide A. Chemical Science, 12(15), 5534–5543. https://doi.org/10.1039/D0SC06223E

 

Corcilius, L., Liu, D. Y., Ochoa, J. L., Linington, R. G., & Payne, R. J. (2018). Synthesis and evaluation of analogues of the glycinocin family of calcium-dependent antibiotics. Organic & Biomolecular Chemistry, 16(29), 5310–5320. https://doi.org/10.1039/C8OB01268G

 

Deen, M. C., Proceviat, C., Shan, X., Wu, L., Shen, D. L., Davies, G. J., & Vocadlo, D. J. (2020). Selective Fluorogenic β-Glucocerebrosidase Substrates for Convenient Analysis of Enzyme Activity in Cell and Tissue Homogenates. ACS Chemical Biology, 15(4), 824–829. https://doi.org/10.1021/acschembio.9b01044

 

Hawkins, P. M. E., Liu, D. Y., Linington, R. G., & Payne, R. J. (2021). Solid-phase synthesis of coralmycin A/epi-coralmycin A and desmethoxycoralmycin A. Organic & Biomolecular Chemistry, 19(28), 6291–6300. https://doi.org/10.1039/D1OB01062J

 

Meek, R., Blaza, J., Busmann, J., Alteen, M., Vocadlo, D., & Davies, G. (2021). Cryo-EM provides insights into the dimer arrangement of OGT. Revised manuscript invited.

 

Tavassoly, O., Sade, D., Bera, S., Shaham-Niv, S., Vocadlo, D. J., & Gazit, E. (2018). Quinolinic Acid Amyloid-like Fibrillar Assemblies Seed α-Synuclein Aggregation. Journal of Molecular Biology, 430(20), 3847–3862. https://doi.org/10.1016/j.jmb.2018.08.002

 

Tavassoly, O., Yue, J., & Vocadlo, D. J. (2021). Pharmacological inhibition and knockdown of O-GlcNAcase reduces cellular internalization of α-synuclein preformed fibrils. The FEBS Journal, 288(2), 452–470. https://doi.org/10.1111/febs.15349

 

Ueoka, R., Bhushan, A., Probst, S. I., Bray, W. M., Lokey, R. S., Linington, R. G., & Piel, J. (2018). Genome-Based Identification of a Plant-Associated Marine Bacterium as a Rich Natural Product Source. Angewandte Chemie International Edition, 57(44), 14519–14523. https://doi.org/10.1002/anie.201805673

 

Zhu, Y., Shan, X., Safarpour, F., Erro Go, N., Li, N., Shan, A., Huang, M. C., Deen, M., Holicek, V., Ashmus, R., Madden, Z., Gorski, S., Silverman, M. A., & Vocadlo, D. J. (2018). Pharmacological Inhibition of O-GlcNAcase Enhances Autophagy in Brain through an mTOR-Independent Pathway. ACS Chemical Neuroscience, 9(6), 1366–1379. https://doi.org/10.1021/acschemneuro.8b00015